Synthesis of Gd2O3 nanoparticles for MRI contrast agents
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چکیده
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Synthesized Gd2O3 nanoparticles as contrast agent
Introduction: Gd (III) ion has been known to be the best metal ion in the periodic table that can be used as a T1 MRI contrast agent. Gadolinium have 7 unpaired electrons and these electrons can make magnetic area. No other metal ions possess unpaired electron more than this. CAs based on the element Gd are classified as “positive”, by opposition to “negative” CAs. Nowadays, G...
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Magnetic resonance imaging (MRI) has been widely used to diagnose various diseases. As a positive MRI contrast agent, gadolinium oxide (Gd2O3) is the most promising one due to its paramagnetism and good biocompatibility. However, post-modification on hydrophobic Gd2O3 nanoparticles (NPs) often yield water soluble nanocomposites with some problems: particles aggregation which reduces the number ...
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